The genomic sequence of the Chinese hamster ovary (CHO) K1 cell line (Cricetulus griseus).

Dataset type: Genomic
Data released on July 20, 2011

Xu X; Nagarajan H; Lewis NE; Pan S; Cai Z; Liu X; Chen W; Xie M; Wang W; Hammond S; Andersen MR; Neff N; Passarelli B; Koh W; Fan HC; Wang J; Gui Y; Lee KH; Betenbaugh MJ; Quake SR; Famili I; Palsson BO; Wang J (2011): The genomic sequence of the Chinese hamster ovary (CHO) K1 cell line (Cricetulus griseus). GigaScience. http://dx.doi.org/10.5524/100009

DOI10.5524/100009

Chinese hamster ovary (CHO) K1 cells are a cell line cultured from the ovary of the Chinese hamster (Cricetulus griseus). CHO cells are often used in biological and medical studies and commercially in the production of therapeutic proteins, which contribute significantly to the $100 billion biopharmaceutical market. BGI sequenced the CHO K1 genome genome using next-generation sequencing technology, assembling a 2.45G genome with 24,383 predicted genes.

Additional details

Read the peer-reviewed publication(s):

Xu, X., Nagarajan, H., Lewis, N. E., Pan, S., Cai, Z., Liu, X., … Wang, J. (2011). The genomic sequence of the Chinese hamster ovary (CHO)-K1 cell line. Nature Biotechnology, 29(8), 735–741. doi:10.1038/nbt.1932 (PubMed: 21804562)

Additional information:

http://www.chogenome.org/

Accessions (data included in GigaDB):

GENBANK: AFTD00000000

Accessions (data not in GigaDB):

SRA: SRP007645
SRA: SRP007625





Sample IDTaxonomic IDCommon NameGenbank NameScientific NameSample Attributes
CHO K110029Chinese hamsterChinese hamsterCricetulus griseus
Displaying 1-1 of 1 Sample(s).




File NameSample IDData TypeFile FormatSizeRelease Date 
CHO K1Sequence assemblyFASTA643.59 MB2011-07-20
CHO K1Coding sequenceFASTA33.88 MB2011-07-20
CHO K1AnnotationGFF29.32 MB2011-07-20
CHO K1Protein sequenceFASTA13.01 MB2011-07-20
ReadmeTEXT0.7 KB2011-07-20
Displaying 1-5 of 5 File(s).
Date Action
October 18, 2015 File CHO_0811.scafSeq.FG.gz updated
October 18, 2015 File CHO.spliced.cds.fa.2010-12-06 updated
October 22, 2015 File CHO_0811.scafSeq.FG.gz updated
November 2, 2015 File CHO.spliced.gff.2010-12-06 updated
November 2, 2015 File CHO_0811.scafSeq.FG.gz updated