The genomic sequence of the Chinese hamster ovary (CHO) K1 cell line (Cricetulus griseus).
Dataset type: Genomic
Data released on July 20, 2011
Xu X; Nagarajan H; Lewis NE; Pan S; Cai Z; Liu X; Chen W; Xie M; Wang W; Hammond S; Andersen MR; Neff N; Passarelli B; Koh W; Fan HC; Wang J; Gui Y; Lee KH; Betenbaugh MJ; Quake SR; Famili I; Palsson BO; Wang J (2011): The genomic sequence of the Chinese hamster ovary (CHO) K1 cell line (Cricetulus griseus). GigaScience. http://dx.doi.org/10.5524/100009
Chinese hamster ovary (CHO) K1 cells are a cell line cultured from the ovary of the Chinese hamster (Cricetulus griseus). CHO cells are often used in biological and medical studies and commercially in the production of therapeutic proteins, which contribute significantly to the $100 billion biopharmaceutical market. BGI sequenced the CHO K1 genome genome using next-generation sequencing technology, assembling a 2.45G genome with 24,383 predicted genes.
Read the peer-reviewed publication(s):
Xu, X., Nagarajan, H., Lewis, N. E., Pan, S., Cai, Z., Liu, X., … Wang, J. (2011). The genomic sequence of the Chinese hamster ovary (CHO)-K1 cell line. Nature Biotechnology, 29(8), 735–741. doi:10.1038/nbt.1932
Accessions (data generated as part of this study):