Help Login Create account

Data released on November 12, 2011

Genomic data from the roundworm Ascaris suum.

Anderson, G, A; Campbell, B, E; Cantacessi, C; Chen, F; Fang, X; Geldhof, P; Hall, R, S; Harris, T, W; Jex, A, R; Kang, Y; Li, B; Li, Y; Liu, S; Nejsum, P; Ranganathan, S; Schwarz, E, M; Sternberg, P, W; Vlaminck, J; Wang, J; Wang, J; Wang, T; Wu, X; Xiong, Z; Xu, X; Yang, H; Yang, L; Young, N, D; Zeng, N; Zhang, G; Gasser, R, B (2011): Genomic data from the roundworm Ascaris suum. GigaScience. http://dx.doi.org/10.5524/100017 RIS BibTeX Text

Available here is the draft genome for Ascaris suum, a roundworm species that infects pigs. It is a valuable resource for therapy and diagnostic test development for both Ascaris suum infection of pigs, and also human infection by the closely related species A. lumbricoides. The A. suum genome was sequenced at ~80-fold coverage to generate an approximately 273 million base genome sequence encoding 18,542 protein-coding genes. Compared to other metazoan genomes, it has low repeat content (4.4%). Compared with other parasitic free-living roundworms and C. elegan, A. suum shares the highest homology with Brugia malayi, another animal parasite. The A. suum secretome (consisting of around 750 molecules) is rich in peptidases linked to the penetration and degradation of host tissue, and an assemblage of molecules likely to modulate or evade host immune responses. This genome provides a comprehensive resource to the scientific community and a foundation for developing new and urgently needed therapeutic intervention drugs, vaccines and diagnostic tests) against ascariasis and other nematodiases.

Contact Submitter

Related manuscripts:

doi:10.1038/nature10553 (PubMed: 22031327)

Accessions (data not in GigaDB):

SRA: SRP010159

Genomic

http://gigadb.org/images/data/cropped/100017_Ascaris.jpg

Samples: Table Settings

Columns:

Common Name
Scienfic Name
Sample Attributes
Taxonomic ID
Genbank Name

Sample IDTaxonomic IDCommon NameGenbank NameScientific NameSample Attributes
A. suum6253Pig roundwormpig roundwormAscaris suum
Displaying 1-1 of 1 Sample(s).

Files: (FTP site) Table Settings

Columns:

File Description
Sample ID
File Type
File Format
Size
Release Date
Download Link
File Attributes

File NameSample IDFile TypeFile FormatSizeRelease Date 
A. suumCoding sequenceFASTA5.61 MB2011-11-12
A. suumAnnotationGFF1.37 MB2011-11-12
A. suumProtein sequenceFASTA3.64 MB2011-11-12
A. suumSequence assemblyFASTA79.48 MB2011-11-12
ReadmeTEXT0.29 KB2011-11-12
Displaying 1-5 of 5 File(s).

Other datasets you might like: