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Data released on December 19, 2011

Genomic data from chronic hepatitis B infected humans and healthy controls.

Gao, Z; Huang, W; Li, Q; Liao, Q; Pei, Y; Peng, L; Wang, J; Wang, Y; Zhao, Q (2011): Genomic data from chronic hepatitis B infected humans and healthy controls. GigaScience. http://dx.doi.org/10.5524/100029 RIS BibTeX Text

Chronic hepatitis B (CHB) infection remains endemic in large parts of the world and, as such, is a major global health issue. However, a thorough understanding of the genetic variants involved in CHB infection susceptibility remains lacking. This dataset comprises the raw exome sequencing data, SNP sets and InDel sets for 50 CHB patients and 40 healthy controls. The exome sequences were captured by NimbleGen2.1M array targeting 34 Mb of the human genome, containing 180,000 coding exons and 551 miRNA genes. The enriched library was then sequenced on Illumina HighSeq2000 and sequencing reads were aligned to human reference genome (NCBI build 36.3). The average sequencing depth per sample is 43X after the removal of read duplicates. These data provide a resource for identifying genetic variants predisposing humans to CHB infections.

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Related manuscripts:

doi:10.1002/hep.25850 (PubMed: 22610944)

Accessions (data included in GigaDB):

SRA: SRA048741

Genomic

http://gigadb.org/images/data/cropped/100029_Hepatitis-B.jpg

Samples: Table Settings

Columns:

Common Name
Scienfic Name
Sample Attributes
Taxonomic ID
Genbank Name

Sample IDTaxonomic IDCommon NameGenbank NameScientific NameSample Attributes
13669606HumanhumanHomo sapiens Age:45
Disease status:DOID:2043
Sex:male
14069606HumanhumanHomo sapiens Age:41
Disease status:DOID:2043
Sex:male
14119606HumanhumanHomo sapiens Age:54
Disease status:DOID:2043
Sex:male
14619606HumanhumanHomo sapiens Age:47
Disease status:DOID:2043
Sex:female
15499606HumanhumanHomo sapiens Age:35
Disease status:DOID:2043
Sex:male
16369606HumanhumanHomo sapiens Age:34
Disease status:DOID:2043
Sex:male
16439606HumanhumanHomo sapiens Age:38
Disease status:DOID:2043
Sex:male
17409606HumanhumanHomo sapiens Age:37
Disease status:DOID:2043
Sex:male
17449606HumanhumanHomo sapiens Age:45
Disease status:DOID:2043
Sex:male
17509606HumanhumanHomo sapiens Age:46
Disease status:DOID:2043
Sex:male
Displaying 1-10 of 90 Sample(s).

Files: (FTP site) Table Settings

Columns:

File Description
Sample ID
File Type
File Format
Size
Release Date
Download Link
File Attributes

File NameSample IDFile TypeFile FormatSizeRelease Date 
1366Genome sequenceFASTQ1.28 GB2012-07-12
1366Genome sequenceFASTQ1.24 GB2012-07-12
1406Genome sequenceFASTQ1.23 GB2012-07-12
1406Genome sequenceFASTQ1.2 GB2012-07-12
1933Genome sequenceFASTQ1.19 GB2012-07-12
1933Genome sequenceFASTQ1.16 GB2012-07-12
3128Genome sequenceFASTQ1.05 GB2012-07-12
3128Genome sequenceFASTQ1.02 GB2012-07-12
1740Genome sequenceFASTQ1.05 GB2012-07-12
1740Genome sequenceFASTQ1.04 GB2012-07-12
Displaying 1-10 of 464 File(s).

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