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Data released on August 18, 2016

Genome of the ocean sunfish (Mola mola).

Brenner, S; Lee, A, P; Li, C; Lian, M, M; Pan, H; Ravi, V; Tay, B; Venkatesh, B; Wang, J; Yang, H; Yu, H; Zhang, G (2016): Genome of the ocean sunfish (Mola mola). GigaScience Database. http://dx.doi.org/10.5524/100214 RIS BibTeX Text

The ocean sunfish (Mola mola) which can grow up to a length of 2.7 m and weigh 2.3 tons is the world’s largest bony fish. It exhibits an extremely fast growth rate and possesses an endoskeleton made up largely of cartilage. Another unique feature of the sunfish is the loss of caudal fin which is replaced by a broad and stiff lobe resulting in the characteristic truncated appearance of the fish. To get an insight into the genomic bases of these derived phenotypes, we sequenced the ocean sunfish genome and performed comparative analysis with other teleost genomes. Several ocean sunfish genes involved in the GH/IGF1 axis signaling pathway were found to be under positive selection or accelerated evolution, which might explain its fast growth rate and large body size. A number of genes associated with the extracellular matrix, some of which are involved in the regulation of bone and cartilage development, have also undergone positive selection or accelerated evolution. The ocean sunfish contains seven Hox clusters similar to fugu but contains more Hox genes than fugu. Thus, it appears that the caudal fin loss in ocean sunfish is not associated with the loss of any specific Hox gene. Our analyses provide insights into the molecular basis of the fast growth rate and large size of the sunfish. The high-quality genome assembly generated in this study should facilitate further studies of this ‘natural mutant’.

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Related manuscripts:

doi:10.1186/s13742-016-0144-3

Accessions (data included in GigaDB):

BioProject: PRJNA305960

Keywords:

Ocean sunfish, Mola mola, growth rate, body size, cartilaginous skeleton, positive selection 

Genomic

http://gigadb.org/images/data/cropped/100214.jpg

Samples: Table Settings

Columns:

Common Name
Scienfic Name
Sample Attributes
Taxonomic ID
Genbank Name

Sample IDTaxonomic IDCommon NameGenbank NameScientific NameSample Attributes
sunfish blood94237 ocean sunfishMola mola Description:The sunfish blood sample was collected...
Alternative accession-BioProject:PRJNA305960
Alternative names:SRA319445 and MBDK00000000
...
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T295994237 ocean sunfishMola mola Analyte type:DNA
Life stage:Adult
Description:Ocean sunfish (Mola mola) fin clip sam...
...
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T297994237 ocean sunfishMola mola Analyte type:DNA
Life stage:Adult
Description:Ocean sunfish (Mola mola) fin clip sam...
...
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Displaying 1-3 of 3 Sample(s).

Files: (FTP site) Table Settings

Columns:

File Description
Sample ID
File Type
File Format
Size
Release Date
Download Link
File Attributes

File NameSample IDFile TypeFile FormatSizeRelease Date 
OtherUNKNOWN1.3 KB2016-08-04
AnnotationGFF53.56 MB2016-08-04
AnnotationGFF24.83 MB2016-08-04
AnnotationGFF43.25 MB2016-08-04
AnnotationGFF16.94 MB2016-08-04
AnnotationGFF14.18 MB2016-08-04
AnnotationGFF12.25 MB2016-08-04
AnnotationGFF11.49 MB2016-08-04
AnnotationGFF15.95 MB2016-08-04
AnnotationGFF17.58 MB2016-08-04
Displaying 1-10 of 22 File(s).

History:

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