Supporting data for "Shotgun Metagenomics of 250 Adult Twins Reveals Genetic and Environmental Impacts on the Gut Microbiome"

Dataset type: Metagenomic
Data released on November 02, 2016

Xie H; Guo R; Zhong H; Feng Q; Lan Z; Qin B; Ward KJ; Jackson MA; Xia Y; Chen X; Chen B; Xia H; Xu C; Li F; Xu X; Al-Aama JY; Yang H; Wang J; Kristiansen K; Wang J; Steves CJ; Bell JT; Li J; Spector TD; Jia H (2016): Supporting data for "Shotgun Metagenomics of 250 Adult Twins Reveals Genetic and Environmental Impacts on the Gut Microbiome" GigaScience. http://dx.doi.org/10.5524/100253

DOI10.5524/100253

The first large cohort of shotgun sequenced dataset for the gut microbiome in twins, including 250 adult twins in the TwinsUK registry, leading to an updated reference gene catalog of 11.4 million genes. Heritability was identified in microbial taxa and potential functions, and sharing of microbial single-nucleotide polymorphisms (SNPs) between twins were demonstrated, all underscoring the value of twins for the understanding of the genetic and environmental underpinnings of the gut microbiome.

Additional details

Read the peer-reviewed publication(s):

Xie, H., Guo, R., Zhong, H., Feng, Q., Lan, Z., Qin, B., … Jia, H. (2016). Shotgun Metagenomics of 250 Adult Twins Reveals Genetic and Environmental Impacts on the Gut Microbiome. Cell Systems, 3(6), 572–584.e3. doi:10.1016/j.cels.2016.10.004

Related datasets:

doi:10.5524/100253 Cites doi:10.5524/100064

Accessions (data referenced by this study):

BioProject: PRJEB9576





Sample IDTaxonomic IDCommon NameGenbank NameScientific NameSample Attributes
35365408170Human gut metagenome human gut metagenome Geographic location (country and/or sea,region):ENGLISH
Sex:FEMALE
Age:62
35366408170Human gut metagenome human gut metagenome Geographic location (country and/or sea,region):ENGLISH
Sex:FEMALE
Age:62
35387408170Human gut metagenome human gut metagenome Geographic location (country and/or sea,region):ENGLISH
Sex:FEMALE
Age:50
35388408170Human gut metagenome human gut metagenome Geographic location (country and/or sea,region):ENGLISH
Sex:FEMALE
Age:50
35389408170Human gut metagenome human gut metagenome Geographic location (country and/or sea,region):ENGLISH
Sex:FEMALE
Age:65
35390408170Human gut metagenome human gut metagenome Geographic location (country and/or sea,region):ENGLISH
Sex:FEMALE
Age:65
35391408170Human gut metagenome human gut metagenome Geographic location (country and/or sea,region):ENGLISH
Sex:FEMALE
Age:65
35392408170Human gut metagenome human gut metagenome Geographic location (country and/or sea,region):ENGLISH
Sex:FEMALE
Age:65
35505408170Human gut metagenome human gut metagenome Geographic location (country and/or sea,region):ENGLISH
Sex:FEMALE
Age:42
35506408170Human gut metagenome human gut metagenome Geographic location (country and/or sea,region):ENGLISH
Sex:FEMALE
Age:42
Displaying 1-10 of 250 Sample(s).




File NameSample IDData TypeFile FormatSizeRelease Date 
Coding sequenceFASTA2.66 GB2016-11-02
35365Genome assemblyUNKNOWN77.76 MB2016-11-02
35366Genome assemblyUNKNOWN63.99 MB2016-11-02
35387Genome assemblyUNKNOWN88.69 MB2016-11-02
35388Genome assemblyUNKNOWN77.12 MB2016-11-02
35389Genome assemblyUNKNOWN30.69 MB2016-11-02
35390Genome assemblyUNKNOWN40.85 MB2016-11-02
35391Genome assemblyUNKNOWN86.62 MB2016-11-02
35392Genome assemblyUNKNOWN101.32 MB2016-11-02
35505Genome assemblyUNKNOWN65.08 MB2016-11-02
Displaying 1-10 of 260 File(s).
Date Action
November 2, 2016 Dataset publish
November 2, 2016 Link added : BioProject:PRJEB9576
November 2, 2016 Link updated : BioProject:PRJEB9576
November 15, 2016 File readme.txt updated
November 15, 2016 File readme.txt updated