Supporting data for "16GT: a fast and sensitive variant caller using a 16-genotype probabilistic model"
Dataset type: Software
Data released on June 16, 2017
16GT is a variant caller for Illumina whole-genome and whole-exome sequencing data. It uses a new 16-genotype probabilistic model to unify SNP and indel calling in a single variant calling algorithm. In benchmark comparisons with five other widely used variant callers on a modern 36-core server, 16GT demonstrated improved sensitivity in calling SNPs, and it provided comparable sensitivity and accuracy for calling indels as compared to the GATK HaplotypeCaller. 16GT is available at https://github.com/aquaskyline/16GT.
Read the peer-reviewed publication(s):
Luo, R., Schatz, M. C., & Salzberg, S. L. (2017). 16GT: a fast and sensitive variant caller using a 16-genotype probabilistic model. GigaScience, 6(7). doi:10.1093/gigascience/gix045