Supporting data for "Molecular modularity and asymmetry of the molluscan mantle revealed by a gene expression atlas"

Dataset type: Transcriptomic
Data released on May 03, 2018

Herlitze I; Marie B; Marin F; Jackson DJ (2018): Supporting data for "Molecular modularity and asymmetry of the molluscan mantle revealed by a gene expression atlas" GigaScience Database. http://dx.doi.org/10.5524/100436

DOI10.5524/100436

Conchiferan molluscs construct a biocalcified shell that likely supported much of their evolutionary success. However beyond broad proteomic and transcriptomic surveys of molluscan shells and the shell-forming mantle tissue, little is known of the spatial and ontogenetic regulation of shell fabrication. In addition, most efforts have been focused on species that deposit nacre, which is at odds with the majority of conchiferan species that fabricate shells using a crossed lamellar microstructure, sensu lato. By combining proteomic and transcriptomic sequencing with in situ hybridisation we have identified a suite of gene products associated with the production of the crossed-lamellar shell in Lymnaea stagnalis. With this spatial expression data we are able to generate novel hypotheses of how the adult mantle tissue coordinates the deposition of the calcified shell. These hypotheses include functional roles for unusual and otherwise difficult to study proteins such as those containing repetitive low complexity domains (RLCDs). The spatial expression readouts of the shell-forming genes we studied also reveal cryptic patterns of asymmetry and modularity in the shell-forming cells of larvae and adult mantle tissue. This molecular modularity of the shell-forming mantle tissue hints at an intimate association between structure, function and evolvability and may provide an elegant explanation for the evolutionary success of the second largest phylum among the Metazoa.

Additional details

Read the peer-reviewed publication(s):

Herlitze, I., Marie, B., Marin, F., & Jackson, D. J. (2018). Molecular modularity and asymmetry of the molluscan mantle revealed by a gene expression atlas. GigaScience. doi:10.1093/gigascience/giy056

Accessions (data included in GigaDB):

PRIDE: PXD008547
BioProject: PRJNA420639





Sample IDTaxonomic IDCommon NameGenbank NameScientific NameSample Attributes
SAMN081172146523 great pond snailLymnaea stagnalis Description:RNA extracted from L. stagnalis mantle...
Alternative names:great pond snail
Alternative accession-BioProject:PRJNA420639
...
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SAMN081172156523 great pond snailLymnaea stagnalis Description:RNA extracted from L. stagnalis mantle...
Alternative names:great pond snail
Alternative accession-BioProject:PRJNA420639
...
+
SAMN087093706523 great pond snailLymnaea stagnalis Description:RNA extracted from L. stagnalis cephal...
Alternative names:great pond snail
Alternative accession-BioProject:PRJNA420639
...
+
SAMN087093716523 great pond snailLymnaea stagnalis Description:RNA extracted from L. stagnalis cephal...
Alternative names:great pond snail
Alternative accession-BioProject:PRJNA420639
...
+
SAMN087093726523 great pond snailLymnaea stagnalis Description:RNA extracted from L. stagnalis CNS
Alternative names:great pond snail
Alternative accession-BioProject:PRJNA420639
...
+
SAMN087093736523 great pond snailLymnaea stagnalis Description:RNA extracted from L. stagnalis foot
Alternative names:great pond snail
Alternative accession-BioProject:PRJNA420639
...
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SAMN087093746523 great pond snailLymnaea stagnalis Description:RNA extracted from L. stagnalis Buccal...
Alternative names:great pond snail
Alternative accession-BioProject:PRJNA420639
...
+
SAMN087093756523 great pond snailLymnaea stagnalis Description:RNA extracted from L. stagnalis 42 hou...
Alternative names:great pond snail
Alternative accession-BioProject:PRJNA420639
...
+
SAMN087093766523 great pond snailLymnaea stagnalis Description:RNA extracted from L. stagnalis 52 hou...
Alternative names:great pond snail
Alternative accession-BioProject:PRJNA420639
...
+
SAMN087093776523 great pond snailLymnaea stagnalis Description:RNA extracted from L. stagnalis 67 hou...
Alternative names:great pond snail
Alternative accession-BioProject:PRJNA420639
...
+
Displaying 1-10 of 10 Sample(s).




File NameSample IDData TypeFile FormatSizeRelease Date 
MS supplemental fileEXCEL10.82 KB2018-07-04
MS supplemental fileTEXT17.81 KB2018-07-04
MS supplemental fileEXCEL17.99 KB2018-07-04
MS supplemental fileTEXT27.51 KB2018-07-04
FASTAFASTA27.51 KB2018-04-27
MS supplemental fileEXCEL29 KB2018-07-04
MS supplemental fileEXCEL40.33 KB2018-07-04
MS supplemental fileEXCEL43.95 KB2018-07-04
MS supplemental fileUNKNOWN54.9 KB2018-07-04
MS supplemental fileEXCEL91.15 KB2018-07-04
Displaying 1-10 of 1024 File(s).
Funding body Awardee Award ID Comments
Deutsche Forschungsgemeinschaft DJ Jackson JA 2108/2-1
Deutsche Forschungsgemeinschaft DJ Jackson JA 2108/6-1
Volkswagen Foundation (DE) DJ Jackson 92075
Date Action
May 3, 2018 Dataset publish
July 4, 2018 47 manuscript supplemental files added to dataset
July 9, 2018 Manuscript Link added : 10.1093/gigascience/giy056